BMP6 Recombinant Antibody
Product Specifications
Background
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Differential expression of this gene may be associated with progression of breast and prostate cancer. Mutations in this gene may be associated with iron overload in human patients. [provided by RefSeq, Jul 2016]
Synonyms
Bone Morphogenic Protein 6; Decapentaplegic vegetal related; DVR6; BMP 6; BMP-6; TGFB related vegetal related growth factor; Transforming growth factor beta; Vegetal related (TGFB related) cytokine; Vg related sequence; VGR; VGR1; BMP6_HUMAN.
Gene ID
654
Swiss Prot
P22004
Cellular Locus
Secreted
Host
Rabbit
Cross Reactivity
Human, Rat
Target
BMP6
Clonality
Recombinant
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human BMP6
Applications
WB, IF
Purification
Purified by Protein A.
Concentration
1mg/ml
Dilution
WB (1:300-5000), IF ()
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Prediction Reactivity
Mouse
Gene ID URL
654
Isotype
IgG/Kappa
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