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SOX1 Recombinant Antibody, Biotin Conjugated

Product Specifications

Background

Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.

Synonyms

Sex determining region Y box 1 antibody, sox1 antibody, SOX1_HUMAN antibody, SRY antibody, SRY box containing gene 1 antibody, SRY related HMG box gene 1 antibody, Transcription factor Sox-1 antibody

Gene ID

6656

Swiss Prot

O00570

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human

Target

SOX1

Clonality

Recombinant

Conjugation

Biotin

Source

Recombinant protein

Applications

IHC-P, IHC-F

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

IHC-P (1:200-400), IHC-F (1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

6656

Isotype

IgG

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