SOX1 Recombinant Antibody
Product Specifications
Background
Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.
Synonyms
Sex determining region Y box 1 antibody, sox1 antibody, SOX1_HUMAN antibody, SRY antibody, SRY box containing gene 1 antibody, SRY related HMG box gene 1 antibody, Transcription factor Sox-1 antibody
Gene ID
6656
Swiss Prot
O00570
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human
Target
SOX1
Clonality
Recombinant
Conjugation
Unconjugated
Source
Recombinant protein
Applications
IHC-P, IHC-F, IF, ICC/IF
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
IHC-P (1:200-400), IHC-F (1:100-500), IF (), ICC/IF (1:50-100)
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
6656
Isotype
IgG
Curated Selection
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