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P2Y6 Recombinant Antibody, AbBy Fluor™ 488 Conjugated

Product Specifications

Background

P2Y6 belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. Four transcript variants encoding the same isoform have been identified for this gene. Receptor for extracellular UDP > UTP > ATP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.

Synonyms

P2Y purinoceptor 6; P2Y6; P2RY6

Gene ID

5031

Swiss Prot

Q15077

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human

Target

P2Y6

Clonality

Recombinant

Conjugation

AbBy Fluor™ 488

Source

Synthetic peptide corresponding to N-terminal human P2Y6.

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

499nm/519nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

5031

Isotype

IgG

Curated Selection

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