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CENPC1 Recombinant Antibody, APC Conjugated

Product Specifications

Background

Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions.

Synonyms

CENP-C 1; CENP-C; CENPC_HUMAN; CENPC1; Centromere autoantigen C; Centromere autoantigen C1; Centromere protein C 1; ICEN7; Interphase centromere complex protein 7; MIF2.

Gene ID

1060

Swiss Prot

Q03188

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

CENPC1

Clonality

Recombinant

Conjugation

APC

Source

Recombinant human CENPC1 protein

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

1060

Isotype

IgG

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