Galectin 8 Recombinant Antibody
Product Specifications
Background
Beta-galactoside-binding lectin that acts as a sensor of membrane damage caused by infection and restricts the proliferation of infecting pathogens by targeting them for autophagy. Detects membrane rupture by binding beta-galactoside ligands located on the lumenal side of the endosome membrane; these ligands becoming exposed to the cytoplasm following rupture. Restricts infection by initiating autophagy via interaction with CALCOCO2/NDP52. Required to restrict infection of bacterial invasion such as S.typhimurium. Also required to restrict infection of Picornaviridae viruses. Has a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.
Synonyms
Galectin-8; Po66 carbohydrate-binding protein; Prostate carcinoma tumor antigen 1; Gal-8; Po66-CBP; PCTA-1; LGALS8
Gene ID
3964
Swiss Prot
O00214
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human
Target
LGALS8
Clonality
Recombinant
Conjugation
Unconjugated
Source
Synthetic peptide within human Galectin 8 aa 1-100
Applications
WB, FCM, IHC-P, IF (IHC-P), IF (ICC)
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
WB (1:300-5000), FCM (1:20-100), IHC-P (1:200-400), IF (IHC-P) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Prediction Reactivity
Mouse, Rat
Gene ID URL
3964
Isotype
IgG
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS9398961 Inquire
Goat Uncharacterized Protein C2orf16 (C2ORF16) ELISA Kit
Sign In for Pricing
View Details 