Furin Recombinant Antibody
Product Specifications
Background
Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX (K/R) R consensus motif. Mediates processing of TGFB1, an essential step in TGF-beta-1 activation. Probably cleaves and activates anthrax and diphtheria toxins. Required for H7N1 and H5N1 influenza virus infection probably by cleaving hemagglutinin.
Synonyms
Dibasic-processing enzyme; Paired basic amino acid residue-cleaving enzyme; PACE; FURIN; FUR; PACE; PCSK3
Gene ID
5045
Swiss Prot
P09958
Cellular Locus
Secreted, Cell membrane, Golgi apparatus, Endosome
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
Furin
Clonality
Recombinant
Conjugation
Unconjugated
Source
Recombinant protein within human Furin aa 200-400.
Applications
WB, IHC-P, IHC-F, IF
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
WB (WB (1:500-1:1000) ), IHC-P (IHC-P (1:50-1:100) ), IHC-F (1:100-500), IF ()
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
5045
Isotype
IgG
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