GAB1 Recombinant Antibody
Product Specifications
Background
GAB1 is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR) . Involved in the MET/HGF-signaling pathway.
Synonyms
GRB2-associated-binding protein 1; GRB2-associated binder 1; Growth factor receptor bound protein 2-associated protein 1; GAB1.
Gene ID
2549
Swiss Prot
Q13480
Cellular Locus
Cytoplasm
Host
Rabbit
Target
GAB1
Clonality
Recombinant
Conjugation
Unconjugated
Source
Recombinant protein within human GAB1 aa 400-600
Applications
WB, FCM, IHC-P, IF (IHC-P), IF (ICC)
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
WB (1:300-5000), FCM (1:20-100), IHC-P (1:200-400), IF (IHC-P) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Unmodified
Storage Conditions
Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Prediction Reactivity
Human, Mouse, Rat
Gene ID URL
2549
Isotype
IgG
Curated Selection
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