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HLA-DQA1 Recombinant Antibody

Product Specifications

Background

Major histocompatibility complex, class II, DQ alpha 1, also known as HLA-DQA1, is a human gene present on short arm of chromosome 6 (6p21.3) and also denotes the genetic locus which contains this gene. The protein encoded by this gene is one of two proteins that are required to form the DQ heterodimer, a cell surface receptor essential to the function of the immune system.HLA-DQA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen-presenting cells.

Synonyms

HLA class II histocompatibility antigen; DQ alpha 1 chain; DC-1 alpha chain; DC-alpha; HLA-DCA; MHC class II DQA1; HLA-DQA1; DQA1; DQ-A1; CELIAC1.

Gene ID

3117

Swiss Prot

P01909

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

HLA-DQA1

Clonality

Recombinant

Conjugation

Unconjugated

Source

Recombinant protein within human HLA-DQA1 aa 50-200

Applications

WB, IHC-P, IHC-F, IF

Purification

Purified by Protein A.

Concentration

1ug/ul

Dilution

WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500), IF ()

Buffer

0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

3117

Isotype

IgG

Curated Selection

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