Rad51 Recombinant Antibody
Product Specifications
Background
Participates in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex DNA and forms helical nucleoprotein filaments. Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.
Synonyms
DNA repair protein RAD51 homolog 1; RAD51 homolog A; HsRAD51; hRAD51; RAD51; RAD51A; RECA; BRCC5; FANCR; MRMV2; HsT16930.
Gene ID
5888
Swiss Prot
Q06609
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
Rad51
Clonality
Recombinant
Conjugation
Unconjugated
Source
Recombinant protein within human Rad51 aa 1-150
Applications
WB, IHC-P, IHC-F, IF
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500), IF ()
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Unmodified
Storage Conditions
Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
5888
Isotype
IgG
Curated Selection
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