IKB epsilon Recombinant Antibody
Product Specifications
Background
The protein encoded by this gene binds to components of NF-kappa-B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF-kappa-B by making it available to translocate to the nucleus. Inhibits DNA-binding of NF-kappa-B p50-p65 and p50-c-Rel complexes.
Synonyms
NF-kappa-B inhibitor epsilon; I-kappa-B-epsilon; NF-kappa-BIE; IkB-E; IkB-epsilon; IKB epsilon; IkappaBepsilon; NFKBIE; NFKB inhibitor epsilon
Gene ID
4794
Swiss Prot
O00221
Host
Rabbit
Cross Reactivity
Human
Target
IKB epsilon
Clonality
Recombinant
Conjugation
Unconjugated
Source
Full length protein
Applications
WB, IHC-P, IHC-F, IF
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500), IF ()
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
4794
Isotype
IgG
Curated Selection
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