PMP22 Recombinant Antibody
Product Specifications
Background
PMP22 is a 22 kDa glycoprotein expressed in the compact myelin of the peripheral nervous system. In the peripheral nervous system, PMP 22 is produced by myelinating Schwann cells and is coexpressed with the genes for myelin basic protein (MBP) during nerve development and regeneration. Alterations in the level of this protein cause several genetic human diseases. If the protein is duplicated, patients develop Charcot Marie Tooth disease. If one copy of the gene is deleted, they suffer from the inherited tendency to pressure palsies.
Synonyms
Peripheral myelin protein 22, Growth arrest-specific protein 3, PMP-22, GAS-3, PMP22, GAS3
Gene ID
5376
Swiss Prot
Q01453
Host
Rabbit
Cross Reactivity
Human, Rat
Target
PMP22
Clonality
Recombinant
Conjugation
Unconjugated
Source
Full length protein
Applications
WB
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
5376
Isotype
IgG
Curated Selection
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