KLF4 Recombinant Antibody
Product Specifications
Background
Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.
Synonyms
Krueppel-like factor 4, Epithelial zinc finger protein EZF, Gut-enriched krueppel-like factor, KLF4
Gene ID
9314
Swiss Prot
O43474
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
KLF4
Clonality
Recombinant
Conjugation
Unconjugated
Source
Human KLF4 between 1 to 500 amino acids
Applications
WB, IHC-P, IHC-F, IF, Flow-Cyt, ICC/IF
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500), IF (), Flow-Cyt (1ug/Test), ICC/IF (1:50-100)
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
9314
Isotype
IgG
Curated Selection
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