Actin Recombinant Antibody
Product Specifications
Background
The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects. [provided by RefSeq, Jul 2008]
Synonyms
Actin, alpha skeletal muscle, Alpha-actin-1, ACTA1
Gene ID
58
Swiss Prot
P68133
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat, Zebrafish
Target
Actin
Clonality
Recombinant
Conjugation
Unconjugated
Source
Full length protein
Applications
WB, IP
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
WB (1:300-5000), IP (1-2ug)
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
58
Isotype
IgG
Curated Selection
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