ABCG2 Recombinant Antibody, APC Conjugated
Product Specifications
Background
High-capacity urate exporter functioning in both renal and extrarenal urate excretion. Plays a role in porphyrin homeostasis as it is able to mediates the export of protoporhyrin IX (PPIX) both from mitochondria to cytosol and from cytosol to extracellular space, and cellular export of hemin, and heme. Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. Implicated in the efflux of numerous drugs and xenobiotics: mitoxantrone, the photosensitizer pheophorbide, camptothecin, methotrexate, azidothymidine (AZT), and the anthracyclines daunorubicin and doxorubicin.
Synonyms
ATP-binding cassette sub-family G member 2, Breast cancer resistance protein, CDw338, Mitoxantrone resistance-associated protein, Placenta-specific ATP-binding cassette transporter, URate exporter, CD_antigen: CD338, ABCG2
Gene ID
9429
Swiss Prot
Q9UNQ0
Host
Rabbit
Cross Reactivity
Human
Target
ABCG2
Clonality
Recombinant
Conjugation
APC
Source
Human ABCG2 aa 1-400
Applications
WB, IF
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), IF ()
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
9429
Isotype
IgG
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS9011832 Inquire
Rabbit anti-Schizosaccharomyces pombe (strain 972/24843)(Fission yeast) grx5 Polyclonal Antibody
Ask
View Details 
GTR15230697 1 Vial
Lentiviral mouse Syf2 shRNA (UAS) - Lentiviral mouse Syf2 shRNA (UAS, GFP) (100)
Ask
View Details 
