SUZ12 Recombinant Antibody, APC Conjugated
Product Specifications
Background
Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.
Synonyms
Polycomb protein SUZ12, Chromatin precipitated E2F target 9 protein, Joined to JAZF1 protein, Suppressor of zeste 12 protein homolog, ChET 9 protein, SUZ12
Gene ID
23512
Swiss Prot
Q15022
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
SUZ12
Clonality
Recombinant
Conjugation
APC
Source
Human SUZ12 between 50 to 150 amino acids
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
23512
Isotype
IgG
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