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SUZ12 Recombinant Antibody, Biotin Conjugated

Product Specifications

Background

Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.

Synonyms

Polycomb protein SUZ12, Chromatin precipitated E2F target 9 protein, Joined to JAZF1 protein, Suppressor of zeste 12 protein homolog, ChET 9 protein, SUZ12

Gene ID

23512

Swiss Prot

Q15022

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

SUZ12

Clonality

Recombinant

Conjugation

Biotin

Source

Human SUZ12 between 50 to 150 amino acids

Applications

WB

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

23512

Isotype

IgG

Curated Selection

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