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PAX6 Recombinant Antibody, AbBy Fluor™ 405 Conjugated

Product Specifications

Background

Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity) . Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity) . Isoform 5a appears to function as a molecular switch that specifies target genes.

Synonyms

Paired box protein Pax-6, Aniridia type II protein, Oculorhombin, PAX6

Swiss Prot

P26367

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

250-350/422

Target

PAX6

Clonality

Recombinant

Conjugation

AbBy Fluor™ 405

Source

Human PAX6 between 250 to 350 amino acids

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

401nm/421nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Isotype

IgG

Curated Selection

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