PAX6 Recombinant Antibody
Product Specifications
Background
Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity) . Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity) . Isoform 5a appears to function as a molecular switch that specifies target genes.
Synonyms
Paired box protein Pax-6, Aniridia type II protein, Oculorhombin, PAX6
Swiss Prot
P26367
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
250-350/422
Target
PAX6
Clonality
Recombinant
Conjugation
Unconjugated
Source
Human PAX6 between 250 to 350 amino acids
Applications
WB, IHC-P, IHC-F, IF
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500), IF ()
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Unmodified
Storage Conditions
Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Isotype
IgG
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