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Integrin alpha 2 Recombinant Antibody, AbBy Fluor™ 488 Conjugated

Product Specifications

Background

Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.

Synonyms

Integrin alpha-2, CD49 antigen-like family member B, Collagen receptor, Platelet membrane glycoprotein Ia, VLA-2 subunit alpha, CD_antigen: CD49b, GPIa, ITGA2

Gene ID

3673

Swiss Prot

P17301

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

Integrin alpha 2

Clonality

Recombinant

Conjugation

AbBy Fluor™ 488

Source

Recombinant protein within Human Integrin alpha 2 aa 1-100

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

499nm/519nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

3673

Isotype

IgG

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