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Integrin alpha 2 Recombinant Antibody

Product Specifications

Background

Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.

Synonyms

Integrin alpha-2, CD49 antigen-like family member B, Collagen receptor, Platelet membrane glycoprotein Ia, VLA-2 subunit alpha, CD_antigen: CD49b, GPIa, ITGA2

Gene ID

3673

Swiss Prot

P17301

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

Integrin alpha 2

Clonality

Recombinant

Conjugation

Unconjugated

Source

Recombinant protein within Human Integrin alpha 2 aa 1-100

Applications

WB, IHC-P, IHC-F, IF

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500), IF ()

Buffer

0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

3673

Isotype

IgG

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