Caspase-9 Recombinant Antibody, AbBy Fluor™ 350 Conjugated
Product Specifications
Background
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly (ADP-ribose) polymerase (PARP) . Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
Synonyms
Caspase-9, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, ICE-like apoptotic protease 6, CASP-9, APAF-3, ICE-LAP6, CASP9
Swiss Prot
P55211
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
Caspase-9
Clonality
Recombinant
Conjugation
AbBy Fluor™ 350
Source
Human Caspase-9 aa 200-350
Applications
WB, IF
Purification
Purified by Protein A.
Excitation Emission
346nm/442nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), IF ()
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Isotype
IgG
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC940745-100 1x 100 µL
CD45 / LCA (2B11 + PD7/26), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC940015-500 1x 500 µL
CD56 / NCAM (123C3.D5), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details