F11R/JAM-A/CD321 Recombinant Antibody, AbBy Fluor™ 405 Conjugated

Product Specifications

Background

Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.

Synonyms

Junctional adhesion molecule A; Junctional adhesion molecule 1; Platelet F11 receptor; Platelet adhesion molecule 1; CD321; JAM-A; JAMA; JAM-1; JAM1; PAM-1; F11R

Gene ID

50848

Swiss Prot

Q9Y624

Cellular Locus

Cell membrane, Extracellular domain, Cell junction

Host

Rabbit

Cross Reactivity

Human

Target

F11R/JAM-A/CD321

Clonality

Recombinant

Conjugation

AbBy Fluor™ 405

Source

Human Junctional Adhesion Molecule 1 between 28-241 amino acids

Applications

Purification

Purified by Protein A.

Excitation Emission

401nm/421nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Mouse, Rat

Gene ID URL

50848

Isotype

IgG

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