Elab Fluor® 700 Anti-Human CD197/CCR7 Antibody[G043H7]
Product Specifications
Background
CCR7, also known as CD197, is a chemokine receptor that binds CCL19 and CCL21. CCR7 and its ligands link innate and adaptive immunity by affecting interactions between T cells and dendritic cells and their downstream effect. Naïve T cells enter the lymph node through high endothelial venules, which express CCL21. Dendritic cells and macrophages enter the lymph node through afferent lymphatics. The encounter of T cells and dendritic cells in the T cell zone is CCR7-dependent. In addition, during immunological surveillance, B cells recirculate between B-cell-rich compartments (follicles or B cell zones) in secondary lymphoid organs, surveying for antigen. After antigen binding, B cells move to the boundary of B and T zones to interact with T-helper cells; this B cell migration is directed by CCR7 and its ligands. CCR7-positive cancer cell expression has been associated with lymph node metastasis.
Abbreviation
CD197
Gene ID
1236
UniProt
P32248
Host
Mouse
Reactivity
Human
Target
CMKBR7; EBI1; EVI1; CCR-7; CDw197
Clonality
Monoclonal
Clone
G043H7
Conjugation
Elab Fluor®700
Applications
FCM
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Product Datasheet
https://789.bio/ea/eq1zl0
Product MSDS
https://789.bio/eb/e1KRGC
Recommended Usage
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .
Isotype
Mouse IgG2a, κ
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS2018945-01 24 Strip Well
Mouse Interleukin 18 Binding Protein (IL18BP) ELISA Kit
Ask
View Details 