Phospho-Tau (Thr231) Recombinant Antibody, APC Conjugated
Product Specifications
Background
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Synonyms
Microtubule-associated protein tau, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau, MAPT
Gene ID
4137
Swiss Prot
P10636
Modification Site
Thr231
Host
Rabbit
Cross Reactivity
Mouse, Rat
Target
Phospho-Tau (Thr231)
Clonality
Recombinant
Conjugation
APC
Source
Synthetic phospho-peptide surrounding Thr231 of human Tau
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Prediction Reactivity
Human
Gene ID URL
4137
Isotype
IgG
More Discoveries
Explore Other Products
Browse additional items from our catalog
K4641305 3x 1.0 µg
Cwc15 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)
Sign In for Pricing
View Details 
MBS6327349-01 0.2 mL
NXF1, NT (NXF1, TAP, Nuclear RNA export factor 1, Tip-associated protein, Tip-associating protein, mRNA export factor TAP) (APC)
Sign In for Pricing
View Details 
MBS6327349-02 5x 0.2 mL
NXF1, NT (NXF1, TAP, Nuclear RNA export factor 1, Tip-associated protein, Tip-associating protein, mRNA export factor TAP) (APC)
Sign In for Pricing
View Details