PRNP Recombinant Antibody
Product Specifications
Background
The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity) . Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro) .
Synonyms
Major prion protein, ASCR, PrP27-30, PrP33-35C, CD_antigen: CD230, PrP, PRNP
Gene ID
5621
Swiss Prot
P04156
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
PRNP
Clonality
Recombinant
Conjugation
Unconjugated
Source
C terminal human Prion protein
Applications
WB, FCM, IF (ICC), IHC
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
WB (1:300-5000), FCM (1:20-100), IF (ICC) (1:50-200), IHC ()
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
5621
Isotype
IgG
Curated Selection
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