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N Cadherin Recombinant Antibody, AbBy Fluor™ 594 Conjugated

Product Specifications

Background

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density (By similarity) .

Synonyms

Cadherin-2, CDw325, Neural cadherin, CD_antigen: CD325, N-cadherin, CDH2

Gene ID

1000

Swiss Prot

P19022

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

N Cadherin

Clonality

Recombinant

Conjugation

AbBy Fluor™ 594

Source

Recombinant human N Cadherin between 150 to 250 amino acids

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

590nm/617nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

1000

Isotype

IgG

Curated Selection

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