N Cadherin Recombinant Antibody, AbBy Fluor™ 488 Conjugated
Product Specifications
Background
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density (By similarity) .
Synonyms
Cadherin-2, CDw325, Neural cadherin, CD_antigen: CD325, N-cadherin, CDH2
Gene ID
1000
Swiss Prot
P19022
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
N Cadherin
Clonality
Recombinant
Conjugation
AbBy Fluor™ 488
Source
Recombinant human N Cadherin between 150 to 250 amino acids
Applications
WB, IF
Purification
Purified by Protein A.
Excitation Emission
499nm/519nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), IF ()
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
1000
Isotype
IgG
Curated Selection
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