VEGFR1 Recombinant Antibody, AbBy Fluor™ 350 Conjugated
Product Specifications
Background
VEGF Receptor 1 (also known as FLT) belongs to the src gene family and shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation. The protein acts as a receptor for VEGF, VEGFB and PGF. An alternatively spliced form of the gene produces a soluble protein (sFlt1) which binds vascular endothelial growth factor (VEGF) with high affinity. sFlt1 has a higher affinity for VEGF indicating that it may function as an inhibitor in the VEGF response. VEGF Receptor 1 is specifically expressed in most vascular endothelial cells and peripheral blood monocytes.
Synonyms
Vascular endothelial growth factor receptor 1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor, VEGFR-1, FLT-1, FLT, FLT1
Gene ID
2321
Swiss Prot
P17948
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
VEGFR1
Clonality
Recombinant
Conjugation
AbBy Fluor™ 350
Source
Recombinant protein
Applications
WB, IF
Purification
Purified by Protein A.
Excitation Emission
346nm/442nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), IF ()
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
2321
Isotype
IgG
Curated Selection
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