Bax Recombinant Antibody, PE Conjugated
Product Specifications
Background
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Synonyms
Apoptosis regulator BAX; Bcl-2-like protein 4; Bcl2-L-4; BCL2L4
Gene ID
581
Swiss Prot
Q07812
Cellular Locus
Cytoplasm, Mitochondrion, Membrane bound
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
Bax
Clonality
Recombinant
Conjugation
PE
Source
Recombinant human Bak between 20 to 150 amino acids
Applications
WB, IF, Flow-Cyt
Purification
Purified by Protein A.
Excitation Emission
496,564nm/578nm
Concentration
1 mg/ml
Dilution
WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
581
Isotype
IgG
Curated Selection
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