Bcl-2 Recombinant Antibody
Product Specifications
Background
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) .
Synonyms
Apoptosis regulator Bcl-2; BCL2
Gene ID
596
Swiss Prot
P10415
Cellular Locus
Nucleus, Mitochondrion, Membrane bound, Endoplasmic reticulum
Host
Rabbit
Cross Reactivity
Human
Target
Bcl-2
Clonality
Recombinant
Conjugation
Unconjugated
Source
Recombinant human Bcl-2 between 1 to 200 amino acids.
Applications
WB
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Unmodified
Storage Conditions
Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
596
Isotype
IgG
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