Stat3 Recombinant Antibody, PE-Cy7 Conjugated
Product Specifications
Background
Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6) -responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity) .
Synonyms
APRF; HIES; ADMIO; Signal transducer and activator of transcription 3; Acute-phase response factor; STAT3
Gene ID
6774
Swiss Prot
P40763
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
Stat3
Clonality
Recombinant
Conjugation
PE-Cy7
Source
Recombinant human Stat3 protein, around N-terminal 1-100aa.
Applications
WB, Flow-Cyt
Purification
Purified by Protein A.
Excitation Emission
488nm/780nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), Flow-Cyt (1ug/Test)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
6774
Isotype
IgG
More Discoveries
Explore Other Products
Browse additional items from our catalog
K5020605 3x 1.0 µg
Cbln1 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)
Sign In for Pricing
View Details ![Mouse Monoclonal pan Cytokeratin Antibody (C-11) [DyLight 680]](https://cdn.genprice.uk/genprice/uk/genprice4.webp)
NBP1-48348FR 0.1 mL
Mouse Monoclonal pan Cytokeratin Antibody (C-11) [DyLight 680]
Sign In for Pricing
View Details 
H1905-01C-02 100 µg
Hepatitis B Core, Recombinant (HBV Core, HBcAg)
Sign In for Pricing
View Details