Phospho-IKB alpha (Ser32) Recombinant Antibody
Product Specifications
Background
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
Synonyms
IKBA; MAD-3; NFKBI; NF-kappa-B inhibitor alpha; I-kappa-B-alpha; IkB-alpha; IkappaBalpha; Major histocompatibility complex enhancer-binding protein MAD3; NFKBIA; MAD3
Gene ID
4792
Swiss Prot
P25963
Modification Site
Ser32
Host
Rabbit
Cross Reactivity
Human
Target
Phospho-IKB alpha (Ser32)
Clonality
Recombinant
Conjugation
Unconjugated
Source
Synthetic peptide derived from human IKB alpha (Ser32) around 1-50 amino acids
Applications
WB, ICC/IF
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
WB (1:300-5000), ICC/IF (1:50-100)
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Phosphorylation
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Prediction Reactivity
Mouse
Gene ID URL
4792
Isotype
IgG
Curated Selection
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