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Myosin VIIa Recombinant Antibody

Product Specifications

Background

Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. In retina, myosin VIIa may play a role in trafficking of ribbon-synaptic vesicle complexes and renewal of the outer photoreceptors disks. In inner ear, it may maintain the rigidity of stereocilia during the dynamic movements of the bundle.

Synonyms

Deafness autosomal dominant 11; Deafness autosomal recessive 2; DFNA11; DFNB 2; DFNB2; Myo7a; Myosin 7a; Myosin VIIa; MYU7A; NSRD 2; NSRD2; Ush 1B; Ush1b; Usher syndrome 1B.

Gene ID

17921

Swiss Prot

P97479

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Mouse

Immunogen

861-1035/2215

Target

Myosin VIIa

Clonality

Recombinant

Conjugation

Unconjugated

Source

Recombinant mouse Myosin VIIa protein

Applications

IHC

Purification

Purified by Protein A.

Concentration

1ug/ul

Dilution

IHC ()

Buffer

0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

17921

Isotype

IgG

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