AFP Monoclonal Antibody, APC Conjugated
Product Specifications
Background
Alpha-fetoprotein (AFP) is a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
Synonyms
AFPD; FETA; HPAFP; Alpha-fetoprotein; Alpha-1-fetoprotein; Alpha-fetoglobulin; AFP
Gene ID
174
Swiss Prot
P02771
Host
Mouse
Cross Reactivity
Human, Rat
Target
AFP
Clonality
Monoclonal
Clone
A2
Conjugation
APC
Source
Full length human AFP protein
Applications
WB, IF
Purification
Purified by Protein G.
Excitation Emission
650nm/660nm
Concentration
1ug/ul
Dilution
WB (1:300-5000), IF ()
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
174
Isotype
IgG
Curated Selection
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