AFP Monoclonal Antibody, AbBy Fluor™ 405 Conjugated
Product Specifications
Background
Alpha-fetoprotein (AFP) is a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
Synonyms
AFPD; FETA; HPAFP; Alpha-fetoprotein; Alpha-1-fetoprotein; Alpha-fetoglobulin; AFP
Gene ID
174
Swiss Prot
P02771
Host
Mouse
Cross Reactivity
Human, Rat
Target
AFP
Clonality
Monoclonal
Clone
A2
Conjugation
AbBy Fluor™ 405
Source
Full length human AFP protein
Applications
WB, IF
Purification
Purified by Protein G.
Excitation Emission
401nm/421nm
Concentration
1ug/ul
Dilution
WB (1:300-5000), IF ()
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
174
Isotype
IgG
Curated Selection
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