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GLP-1 (1G9) Monoclonal Antibody, APC Conjugated

Product Specifications

Background

Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. GLP-1 is a potent stimulator of glucose-dependent insulin release. Play important roles on gastric motility and the suppression of plasma glucagon levels. May be involved in thesuppression of satiety and stimulation of glucose disposal in peripheral tissues, independent of the actions of insulin. Have growth-promoting activities on intestinal epithelium. May also regulate the hypothalamic pituitary axis (HPA) via effects on LH, TSH, CRH, oxytocin, and vasopressin. Belongs to the glucagon family.

Synonyms

GCG; GLP 1; glucagon; Glucagon like peptide 1; GRPP; GLP-17-36; GLP-17-37; Oxyntomodulin; OXM; OXY; GLUC_HUMAN.

Host

Mouse

Cross Reactivity

Human, Mouse, Rat

Immunogen

1-31/31

Target

GLP

Clonality

Monoclonal

Clone

1G9

Conjugation

APC

Source

KLH conjugated synthetic peptide derived from human GLP-1

Applications

WB, IF (IHC-P)

Purification

Purified by Protein G.

Excitation Emission

650nm/660nm

Concentration

1ug/ul

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Isotype

IgG

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