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HOPX/LAGY Polyclonal Antibody, Cy5 Conjugated

Product Specifications

Background

Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (By similarity) . May act as a tumor suppressor.

Synonyms

HOD; HOP; OB1; LAGY; TOTO; CAMEO; NECC1; SMAP31; Homeodomain-only protein; Lung cancer-associated Y protein; Not expressed in choriocarcinoma protein 1; Odd homeobox protein 1; HOPX

Gene ID

84525

Swiss Prot

Q9BPY8

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

21-60/73

Target

HOPX/LAGY

Clonality

Polyclonal

Conjugation

Cy5

Source

KLH conjugated synthetic peptide derived from human HOPX/LAGY

Applications

IF, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

625,650nm/670nm

Concentration

1ug/ul

Dilution

IF (), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

84525

Isotype

IgG

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