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TSPAN13 Polyclonal Antibody

Product Specifications

Background

NET-6, also known as TSPAN13 (tetraspanin-13) or TM4SF13 (transmembrane 4 superfamily member 13), is a 204 amino acid multi-pass membrane protein that belongs to the tetraspanin (TM4SF) family. Members of the tetraspanin family are cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth, motility, differentiation, and cancer. Considered molecular facilitators, tetraspanin proteins may regulate vesicle fusion and fission. The gene encoding NET-6 maps to human chromosome 7, which houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.

Synonyms

NET 6; NET6; Tetraspan NET-6; Tetraspanin-13; TM4SF13; Transmembrane 4 superfamily member 13; Transmembrane 4 superfamily member tetraspan NET 6; Tspan-13; Tspan13; TSN13_HUMAN.

Gene ID

27075

Cellular Locus

Extracellular

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

61-160/204

Target

TSPAN13

Clonality

Polyclonal

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human TSPAN13/NET-6

Applications

IHC-P, IHC-F, IF

Purification

Purified by Protein A.

Concentration

1ug/ul

Dilution

IHC-P (IHC-P=1:100-500), IHC-F (IHC-F=1:100-500), IF (IF=1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

27075

Isotype

IgG

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