ASZ1 Polyclonal Antibody
Product Specifications
Background
Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation (By similarity) .
Synonyms
ALP1; GASZ; Orf3; ANKL1; C7orf7; CT1.19; Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1; Ankyrin-like protein 1; Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein; ASZ1
Gene ID
136991
Swiss Prot
Q8WWH4
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Mouse
Immunogen
151-250/475
Target
ASZ1
Clonality
Polyclonal
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human ASZ1
Applications
WB, IHC-P, IF (IHC-P)
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
WB (1:300-5000), IHC-P (1:200-400), IF (IHC-P) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Prediction Reactivity
Human, Rat, Horse
Gene ID URL
136991
Isotype
IgG
Curated Selection
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