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RNF128 Polyclonal Antibody, AbBy Fluor™ 680 Conjugated

Product Specifications

Background

The protein encoded by this gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4 (+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].

Synonyms

E3 ubiquitin protein ligase RNF128; E3 ubiquitin-protein ligase RNF128; FLJ23516; Gene related to anergy in lymphocytes protein; GRAIL; ring finger protein 128; RN128_HUMAN; RNF128.

Gene ID

79589

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

151-260/428

Target

RNF128

Clonality

Polyclonal

Conjugation

AbBy Fluor™ 680

Source

KLH conjugated synthetic peptide derived from human RNF128

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

679nm/702nm

Concentration

1ug/ul

Dilution

WB (WB=1:500-2000), IF (IF=1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

79589

Isotype

IgG

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