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HnRNP U Polyclonal Antibody, AbBy Fluor™ 680 Conjugated

Product Specifications

Background

Heterogeneous nuclear ribonucleoproteins (hnRNPs) are thought to be involved in pre-mRNA processing. However, its role in the regulation of gene expression is as yet poorly understood. Proteins of the heterogeneous nuclear ribonucleoparticles (hnRNP) family form a structurally diverse group of RNA binding proteins implicated in various functions. Recently, hnRNP proteins have been shown to hinder communication between factors bound to different splice sites. Conversely, several reports have described a positive role for some hnRNP proteins in pre-mRNA splicing. hnRNP-U, also termed scaffold attachment factor A (SAF-A), binds to pre-mRNA and nuclear matrix/scaffold attachment region DNA elements.

Synonyms

Heterogeneous nuclear ribonucleoprotein U; hnRNP U; hnRNP U protein; HNRNPU; hnRNPU protein; HNRPU; HNRPU_HUMAN; p120; p120 nuclear protein; pp120; SAF A; SAF-A; SAFA; Scaffold attachment factor A; U21.1; GRIP120; C1orf199

Gene ID

3192

Swiss Prot

Q00839

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat, Others

Immunogen

2-100/825

Target

HnRNP U

Clonality

Polyclonal

Conjugation

AbBy Fluor™ 680

Source

KLH conjugated synthetic peptide derived from human hnRNP U

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

679nm/702nm

Concentration

1ug/ul

Dilution

WB (WB=1:500-2000), IF (IF=1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

3192

Isotype

IgG

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