Hemoglobin Beta Polyclonal Antibody, HRP Conjugated
Product Specifications
Background
The delta (HBD) and beta (HBB) genes are normally expressed in the adult: two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin. Two alpha chains plus two delta chains constitute HbA-2, which with HbF comprises the remaining 3% of adult hemoglobin. Five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon--Ggamma--Agamma--delta--beta-3'. Mutations in the delta-globin gene are associated with beta-thalassemia.
Synonyms
CD113t-C; beta-globin; Hemoglobin subunit beta; Hemoglobin beta chain; HBB; Hemoglobin subunit delta; HBD; Delta-globin; Hemoglobin delta chain
Gene ID
3043; 3045
Swiss Prot
P68871; P02042
Cellular Locus
Cytoplasm, Secreted
Host
Rabbit
Cross Reactivity
Human
Immunogen
51-147/147
Target
Hemoglobin Beta
Clonality
Polyclonal
Conjugation
HRP
Source
KLH conjugated synthetic peptide derived from human Hemoglobin beta
Applications
WB, ELISA
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
WB (1:300-5000), ELISA (1:500-1000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Specificity
Antibody has equal affinity for Human Hemoglobin Beta and Delta
Gene ID URL
3043; 3045
Isotype
IgG
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