Caspase-9 p10 Polyclonal Antibody, Cy5 Conjugated
Product Specifications
Background
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly (ADP-ribose) polymerase (PARP) . Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
Synonyms
MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6; Caspase-9; CASP-9; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; ICE-like apoptotic protease 6; CASP9
Gene ID
842
Swiss Prot
P55211
Cellular Locus
Secreted
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
351-416/416
Target
Caspase-9 p10
Clonality
Polyclonal
Conjugation
Cy5
Source
KLH conjugated synthetic peptide derived from human caspase-9 subunit p10
Applications
WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
625,650nm/670nm
Concentration
1ug/ul
Dilution
WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Prediction Reactivity
Dog, Cow, Pig, Horse, Chicken, Rabbit
Gene ID URL
842
Isotype
IgG
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
HT-50-C-HTR-5 480/pk
50UL HAMILTON CO-RE STYLE CLEAR TIP. 96 TIPS PER RACK, 5 RACKS/PACK, 12 PACKS/CASE
Ask
View Details 
GTR15196471 1 Vial
Lentiviral mouse Slc31a1 shRNA (UAS) - Lentiviral mouse Slc31a1 shRNA (UAS) plasmid
Ask
View Details