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SMC6 Polyclonal Antibody, AbBy Fluor™ 647 Conjugated

Product Specifications

Background

SMC5/6 complex is recruited to nuclease induced double strand breaks (DSBs) and is required for the recruitment of cohesin to DSBs. The human SMC5/6 complex and the SUMO ligase activity of hMMS21 are required for the prevention of DNA damage induced apoptosis by facilitating DNA repair in human cells.

Synonyms

SMC6L1; SMC 6; SMC6; SMC6 protein; SMC6 structural maintenance of chromosomes 6 like 1; Structural maintenance of chromosomes 6; Structural maintenance of chromosomes 6 like 1; Structural maintenance of chromosomes protein 6.

Gene ID

79677

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Rat

Immunogen

155-260/1091

Target

SMC6

Clonality

Polyclonal

Conjugation

AbBy Fluor™ 647

Source

KLH conjugated synthetic peptide derived from human SMC6

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/665nm

Concentration

1ug/ul

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Human, Mouse, Dog, Cow, Sheep, Pig, Horse, Rabbit

Gene ID URL

79677

Isotype

IgG

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