Corin Polyclonal Antibody, AbBy Fluor™ 750 Conjugated

Product Specifications

Background

Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB the B-type natriuretic peptide. Isoform 2: has weaker endopeptidase activity compared to isoform 1.

Synonyms

CRN; ATC2; Lrp4; PEE5; TMPRSS10; Atrial natriuretic peptide-converting enzyme; Corin; Heart-specific serine proteinase ATC2; Pro-ANP-converting enzyme; Transmembrane protease serine 10

Gene ID

10699

Swiss Prot

Q9Y5Q5

Cellular Locus

Secreted, Cell membrane

Host

Rabbit

Cross Reactivity

Human

Immunogen

165-245/1042

Target

Corin

Clonality

Polyclonal

Conjugation

AbBy Fluor™ 750

Source

KLH conjugated synthetic peptide derived from human Corin

Applications

IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

749nm/775nm

Concentration

1ug/ul

Dilution

IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Mouse, Rat, Dog, Pig, Horse

Gene ID URL

10699

Isotype

IgG

Curated Selection

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