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GAS 6 Polyclonal Antibody

Product Specifications

Background

Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.

Synonyms

AXSF; AXLLG; Growth arrest-specific protein 6; GAS-6; AXL receptor tyrosine kinase ligand; GAS6

Gene ID

2621

Swiss Prot

Q14393

Cellular Locus

Secreted

Host

Rabbit

Cross Reactivity

Human, Mouse

Immunogen

551-650/721

Target

GAS 6

Clonality

Polyclonal

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human GAS 6

Applications

WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1ug/ul

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Prediction Reactivity

Rat, Dog, Cow, Pig, Horse, Chicken

Gene ID URL

2621

Isotype

IgG

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