WT1 Polyclonal Antibody, AbBy Fluor™ 555 Conjugated
Product Specifications
Background
Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA.
Synonyms
GUD; AWT1; WAGR; WT33; NPHS4; WIT-2; EWS-WT1; Wilms tumor protein; WT1
Gene ID
7490
Swiss Prot
P19544
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
301-400/449
Target
WT1
Clonality
Polyclonal
Conjugation
AbBy Fluor™ 555
Source
KLH conjugated synthetic peptide derived from human Wilms Tumor Protein
Applications
WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
553nm/568nm
Concentration
1ug/ul
Dilution
WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Prediction Reactivity
Dog, Cow, Sheep, Pig, Chicken
Gene ID URL
7490
Isotype
IgG
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15196098 1 Vial
Lentiviral mouse AI429214 shRNA (UAS) - Lentiviral mouse AI429214 shRNA (UAS) (100)
Ask
View Details 
H5110-08F-APC 200 µL
Histone H2A/s, NT (Histone H2A Type 1-H, HIST1H2AH, HIST1H2AI) (APC) discontinued
Ask
View Details