FOXN1 Polyclonal Antibody, AbBy Fluor™ 750 Conjugated

Product Specifications

Background

Mutations in the winged-helix transcription factor gene at the nude locus in mice and rats produce the pleiotropic phenotype of hairlessness and athymia, resulting in a severely compromised immune system. This gene is orthologous to the mouse and rat genes and encodes a similar DNA-binding transcription factor that is thought to regulate keratin gene expression. A mutation in this gene has been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Alternative splicing in the 5' UTR of this gene has been observed. [provided by RefSeq, Jul 2008].

Synonyms

WHN; RONU; FKHL20; Forkhead box protein N1; Winged-helix transcription factor nude; FOXN1

Gene ID

8456

Swiss Prot

O15353

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

321-420/648

Target

FOXN1

Clonality

Polyclonal

Conjugation

AbBy Fluor™ 750

Source

KLH conjugated synthetic peptide derived from human FOXN1

Applications

WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

749nm/775nm

Concentration

1ug/ul

Dilution

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Dog, Cow, Pig, Horse, Chicken, Rabbit

Gene ID URL

8456

Isotype

IgG

Curated Selection

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