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Factor B Polyclonal Antibody, APC Conjugated

Product Specifications

Background

Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.

Synonyms

BF; FB; BFD; GBG; CFAB; CFBD; PBF2; AHUS4; FBI12; H2-Bf; ARMD14; Complement factor B; C3/C5 convertase; Glycine-rich beta glycoprotein; Properdin factor B; CFB

Gene ID

629

Swiss Prot

P00751

Cellular Locus

Secreted

Host

Rabbit

Cross Reactivity

Mouse, Rat

Immunogen

301-400/764

Target

Factor B

Clonality

Polyclonal

Conjugation

APC

Source

KLH conjugated synthetic peptide derived from human Complement factor-B Bb fragment

Applications

WB, IF (IHC-P)

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

1ug/ul

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

629

Isotype

IgG

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